chitin synthase การใช้

• Some of these are natural products, such as moenomycin, an inhibitor of peptidoglycan glycosyltransferases, the nikkomycins, inhibitors of chitin synthase, and the echinocandins, inhibitors of fungal b-1, 3-glucan synthases.
• Despite their unconventional feeding habits, chitin has been observed in the inner layer of resting spores, and in immature resting spores for some species of " Rozella ", as indicated with calcofluor-white stain as well as the presence of a fungal-specific chitin synthase gene.
• This species has also been reported to produce chaetoatrosin A, a selective inhibitor of chitin synthase II . This enzyme is involved in septum formation and cellular division, and its inhibition by chaetoatrosin A is thought to be the mechanism underlying the antifungal effects of " C . atrobrunneum " culture filtrates against several medically important fungi including " Cryptococcus neoformans ".